Allele/Variant

Tg(CMV-Plaur*)19Lbh

Species

Mus musculus

Symbol

Tg(CMV-Plaur*)19Lbh

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

CMVflox-suPAR-FL

Description

The construct is designed with the CMV-IE enhancer/chicken beta-actin hybrid promoter (CAG; from the pCAGGS vector), a loxP-flanked transcriptional STOP cassette (containing beta galactosidase and a polyadenylation signal), and the soluble form of the murine urokinase-type plasminogen activator receptor (Plaur) gene. The soluble form of Plaur (suPAR) encodes a 60 kDa truncated protein, lacking the glycophosphatidylinositol (GPI) anchored three domain (commonly referred to as D1, D2, D3) protein.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Plaur (Mmu)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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