Allele/Variant

Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz

Species
Mus musculus
Symbol
Tg(Eno2-APP*Ind,-PSEN1*P267S)#Kakiz
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • V717F/P267S
Description
Two transgenes, one expressing a FLAG-tagged beta-c-terminal fragment of human APP with the Indiana mutation (V717F), and another with an HA-tagged full-length presenilin with the P267S mutation, both under the control of the neuron-specific enolase promoter were coinjected to generate the transgenic mice. The pound symbol (#) is used when line is not specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
impaired spatial learningMGI
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Disease Associations