Allele/Variant

Tg(CAG-Mtor*)#Atai

Species
Mus musculus
Symbol
Tg(CAG-Mtor*)#Atai
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CAG-mTORSL1+IT
Description
This transgene consists of the ubiquitous CAG promoter, a floxed neo cassette, and the mutant rat Mtor kinase, which harbors four point mutations in the FKBP12-rapamycin binding and kinase domains (V2198A, L2216H, L2260P, and I2017T) with a FLAG tag at the N terminus. Excision of the floxed neo gene by cre recombinase induces active Mtor expression. The pound symbol (#) is used when a line is not specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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