Allele/Variant

Fosbtm1.1Yun

Species
Mus musculus
Symbol
Fosbtm1.1Yun
Category
allele
Allele of gene
Fosb
Transgenic Constructs
None
Synonyms
  • Fosbd
Description
A floxed neo cassette was inserted in intron 3 and the sequence encoding the alternative splicing donor site for the exonic intron in exon 4 was replaced with tandem stop codons (GTG, AGA to TAG, TGA) via homologous recombination. This prevents the expression of the short transcript but allows expression of the longer transcript that encodes two isoforms (deltaFosb and delta2deltaFosb). Cre-mediated recombination removed the neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations