Sptbn1^{tm1c(EUCOMM)Wtsi}

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Species

Mus musculus

Symbol

Sptbn1^{tm1c(EUCOMM)Wtsi}

Category

allele

Allele of gene

Sptbn1

Transgenic Constructs

None

Synonyms

• Spnb2^co

Description

The L1L2_gt1 cassette was inserted at position 30109028 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 30109932. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations