Allele/Variant

Lgr5tm1.1(cre/ERT2)Npa

Species
Mus musculus
Symbol
Lgr5tm1.1(cre/ERT2)Npa
Category
allele
Allele of gene
Lgr5
Transgenic Constructs
Synonyms
  • Lgr5-EGFP-IRES-CreERT2
  • Lgr5ki
Description
The targeting construct replaced the first 22 amino acids with an EGFP reporter gene, IRES, inducible cre recombinase fusion (cre/ERT2), polyadenylation sequence and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. In situ hybridization confirmed the absence of transcript expression in the intestin, skin and kidney.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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