Version: 8.0.0
Date: Tue Jan 28 2025
Neurog2tm1.1Meg
MGI:5638453
Allele of Neurog2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Neurog2tm1.1Meg

Species
Mus musculus
Symbol
Neurog2tm1.1Meg
Category
allele
Allele of gene
Neurog2
Transgenic Constructs
None
Synonyms
  • Ngn2S231A&S234A
Description
Nucleotide substitution resulted in the amino acid substitution of serine with alanine at positions 231 and 234 (p.S231A, p.S234A), abolishing phosphorylation potential at those residues. Serine codon 218 was changed from TCA to AGC as a silent mutation to create a diagnostic SacI restriction site. Cre-mediated recombination removed a loxP site flanked neomycin resistance gene cassette that was inserted downstream of the gene.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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