This transgene consists of the cytomegalovirus immediate early enhancer-chicken beta-actin hybrid (CAG) promoter, a floxed lacZ gene, wild-type human FUS cDNA, IRES, and EGFP coding sequences. Cre-excision of the loxP flanked lacZ DNA sequence allows for translation of FUS and EGFP. Two lines were generated: 629 and 638. Line 629 was chosen as a representative line.