Allele/Variant

Tg(SFTPC-Il18)AThos

Species
Mus musculus
Symbol
Tg(SFTPC-Il18)AThos
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • SPC-IL-18 Tg
Description
The human surfactant protein C promoter drives the expression of the mouse mature Il18 cDNA fused with the signal peptide from the v-J2-C region of the mouse Igmu-chain in alveolar and bronchiolar epithelial cells. Western blot analysis confirmed expression in the lungs but not other tissues. Four founders were established: A, B, C, and D. Line A is a representative line as lines A, B, and C exhibit similar phenotypes.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations