Allele/Variant

Lonp1tm1b(EUCOMM)Hmgu

Species
Mus musculus
Symbol
Lonp1tm1b(EUCOMM)Hmgu
Category
allele
Allele of gene
Lonp1
Transgenic Constructs
None
Synonyms
None
Description
Cre-mediated excision of the parental Lonp1tm1a(EUCOMM)Hmgu allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal lens morphologyMGI
decreased circulating iron levelMGI
decreased prepulse inhibitionMGI
increased circulating HDL cholesterol levelMGI
preweaning lethality, complete penetranceMGI
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Disease Associations