Allele/Variant

Tg(NEFH-tTA)8Vle

Species
Mus musculus
Symbol
Tg(NEFH-tTA)8Vle
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • NEFH-tTA
Description
The construct consists of ~18 kbp of the human neurofilament heavy polypeptide promoter (NEFH; from BAC RP11-91J21) upstream of the tetracycline-regulated transactivator gene (tTA or "Tet-Off"), followed by a polyA signal. Founder line 8 has its highest tTA expression in developmental late stage of the cortex, cerebellum and hippocampus, with expression also observed in olfactory bulb and in the rest of the brain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations