Allele/Variant

Tg(Ckm-Chrnd*S262T)40Cgz

Species
Mus musculus
Symbol
Tg(Ckm-Chrnd*S262T)40Cgz
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • deltaS6'T
Description
The murine mutant delta subunit of the acetylcholine receptor which has a threonine for serine substitution at position 262 (S262T) of the second transmembrane domain is under the control of the mouse creatine kinase muscle promoter. A neomycin resistance gene was also inserted downstream of the Chrnd cDNA. Four lines were established: 18, 22, 31, and 40. Line 40 has a transgene copy number of about 25 and is the medium expressing line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations