Ptprc^nim

---

Species

Mus musculus

Symbol

Ptprc^nim

Category

allele

Allele of gene

Ptprc

Transgenic Constructs

None

Synonyms

None

Description

ENU mutagenesis induced a C to T point mutation upstream of exon 18 which introduces an introgenic 1 G nucleotide of the sonsensus splice acceptor sequence. The altered splice acceptor results in a frameshift and truncation at exon 18. Flow cytometry confirmed the absence of protein expression on the surface of B lymphocytes.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations