Allele/Variant

Tg(Cd74-Nlrc4*)1Kyas

Species
Mus musculus
Symbol
Tg(Cd74-Nlrc4*)1Kyas
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • mu-Nlrc4
Description
The mouse Nlrc4 cDNA with a mutation equivalent to the human A to C transversion at position 1589 in exon 4 (changing a histidine to a proline at position 443) and three HA tags is under the control of an invariant chain promoter. Three lines were created: 1, 2, and 3. Line one shows an approximate 3.1-fold increase in Nlrc4 levels in the spleen compared to endogenous levels.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations