Version: 8.0.0
Date: Tue Jan 28 2025
Ltbp2tm1.2Tynk
MGI:5698977
Allele of Ltbp2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ltbp2tm1.2Tynk

Species
Mus musculus
Symbol
Ltbp2tm1.2Tynk
Category
allele
Allele of gene
Ltbp2
Transgenic Constructs
None
Synonyms
  • Ltbp2-
Description
The exon 1 coding sequence was flanked by two loxP sequences inserted in the 5' untranslated region of exon 1 and in intron 1. A FRT-flanked neomycin selection cassette located 3' to the loxP site in intron 1 was deleted via Flp-mediated recombination. Cre-mediated recombination removed the loxP flanked exon 1. RT-PCR, Western blot and immunohistochemical analyses revealed no detectable transcripts or proteins in thoracic tissues (e.g. lung and aorta) from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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