Prdm9^tm1.1Kpgn

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Species

Mus musculus

Symbol

Prdm9^tm1.1Kpgn

Category

allele

Allele of gene

Prdm9

Transgenic Constructs

None

Synonyms

• Prdm9^CAST-KI
• Prdm9^Cst

Show All 4

Description

Exon 12, encoding the zinc finger domain, and 55bp of flanking sequence from intron 11 and 106bp of flanking sequence from the 3-prime UTR from the CAST/EiJ sequence of Prdm9 was inserted in place of that of the endogenous sequence in B6(Cg)-Tyr/J derived ES Cells and an FRT flanked neomycin selection cassette was inserted 621bp downstream of the end of exon 12. Breeding to a Cre deleter strain excised the neo cassette.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations