Version: 8.0.0
Date: Tue Jan 28 2025
Prkcdtm1.1Chou
MGI:5699182
Allele of Prkcd
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Prkcdtm1.1Chou

Species
Mus musculus
Symbol
Prkcdtm1.1Chou
Category
allele
Allele of gene
Prkcd
Transgenic Constructs
None
Synonyms
  • AS-PKCdelta
Description
The targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette downstream of exon 13 of the gene. A point mutation, M425A, is introduced in exon 13, which encodes a key residue for determining the selectivity of PKC inhibitors. Cre-mediated recombination removed the floxed neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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