Allele/Variant

Prkcdtm1.1Chou

Species
Mus musculus
Symbol
Prkcdtm1.1Chou
Category
allele
Allele of gene
Prkcd
Transgenic Constructs
None
Synonyms
  • AS-PKCdelta
Description
The targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette downstream of exon 13 of the gene. A point mutation, M425A, is introduced in exon 13, which encodes a key residue for determining the selectivity of PKC inhibitors. Cre-mediated recombination removed the floxed neo cassette.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations