Allele/Variant

Tg(Plp1-HTT*150Q)4aXjl

Species
Mus musculus
Symbol
Tg(Plp1-HTT*150Q)4aXjl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • PLP-150Q
Description
Expression of a cDNA encoding N-terminal human HTT (amino acids 1-212) containing 150 glutamines in the repeat region (150Q) is under the control of the oligodendrocyte specific murine Plp1 promoter. Western blot confirmed formation of aggregated HTT in the brain and selective expression in the brain stem, striatum, and corpus callosum.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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