Allele/Variant

Gas7tm1Slch

Species
Mus musculus
Symbol
Gas7tm1Slch
Category
allele
Allele of gene
Gas7
Transgenic Constructs
None
Synonyms
  • gas7m
Description
A neomycin resistance cassette with a loxP site and stop codons was inserted into exon 6b. Western blot analysis confirmed the absence of full-length protein and low level expression of a truncated protein. A protein degradation assay revealed that the expressed mutant protein is more easily degraded than the wild-type in primary cortical cultured neurons from E16.5 wild-type and homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations