Allele/Variant

Tg(Prnp-MAPT*R406W)21807Dwst

Species
Mus musculus
Symbol
Tg(Prnp-MAPT*R406W)21807Dwst
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • TgTauR406W
Description
The Syrian hamster prion protein promoter drives the expression of the longest form of the human four-repeat tau with the R406W mutation. Lines 21807, 21783, and 21768 were established. RT-PCR confirmed expression of mRNA in the brain and Western blot analysis shows that expression level is about 80% that of the endogenous mouse levels.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
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