Allele/Variant

Brpf1tm1b(EUCOMM)Wtsi

Species
Mus musculus
Symbol
Brpf1tm1b(EUCOMM)Wtsi
Category
allele
Allele of gene
Brpf1
Transgenic Constructs
None
Synonyms
  • Brpf1delta
Description
The L1L2_gt2 cassette was inserted at position 113293068 of Chromosome 6 upstream of the critical exons 4 through 6 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exons 4-6 at position 113294936. The critical exons 4 through 6 are thus flanked by loxP sites. Cre-mediated recombination removed exons 4-6 and left the FRT flanked lacZ/neomycin sequence followed by one loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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