Brpf1^{tm1c(EUCOMM)Wtsi}

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Species

Mus musculus

Symbol

Brpf1^{tm1c(EUCOMM)Wtsi}

Category

allele

Allele of gene

Brpf1

Transgenic Constructs

None

Synonyms

• Brpf1^f

Description

The L1L2_gt2 cassette was inserted at position 113293068 of Chromosome 6 upstream of the critical exons 4 through 6 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exons 4-6 at position 113294936. The critical exons 4 through 6 are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations