Allele/Variant

Tg(Sftpc-Grem1)105Mmyl

Species
Mus musculus
Symbol
Tg(Sftpc-Grem1)105Mmyl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • SPC-lox-gremlin1
Description
This transgene contains the surfactant associated protein C (Sftpc) promoter followed by a loxP-flanked neomycin resistance cassette with a strong translation termination (STOP) signal and the gremlin 1, DAN family BMP antagonist (Grem1) coding sequence. Deletion of the floxed sequence by Cre recombinase in transgenic mice results in Grem1 expression in lung type II epithelial cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
  • Grem1
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations