Plp2^tm1Dva

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Species

Mus musculus

Symbol

Plp2^tm1Dva

Category

allele

Allele of gene

Plp2

Transgenic Constructs

None

Synonyms

• Plp2^-

Description

A LacZ-neo cassette was inserted into exon 1, six codons downstream of the translational start site. Northern blot analysis revealed absence of transcript in primary neurons isolated from hemizygous mutant males. Western blot analysis confirmed the absence of protein expression in mutant retinal tissue.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations