Cc2d2a^tm1Asw

---

Species

Mus musculus

Symbol

Cc2d2a^tm1Asw

Category

allele

Allele of gene

Cc2d2a

Transgenic Constructs

None

Synonyms

• Cc2d2a^-

Description

Exons 6 to 8, shared by all spicing variants of the expressed transcripts, were replaced with a targeting vector containing a beta-gal reporter and a neomycin selection cassette. RT-PCR analysis revealed absence of mRNA transcripts in lung, liver, fore- and hindlimb tissues from newborn (P0) homozygous mutant mice. Immunoblot analysis confirmed the absence of encoded protein in E14 homozygous mutant embryos.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations