Version: 8.0.0
Date: Tue Jan 28 2025
Trp53tm1.1Umol
MGI:5708402
Allele of Trp53
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Trp53tm1.1Umol

Species
Mus musculus
Symbol
Trp53tm1.1Umol
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53R248Q
Description
Exons 4 through 9 were replaced with the corresponding human sequence with a mutation in exon 7 that results in the amino acid substitution of arginine with glutamine at position 248 (p.R248Q). Flp-mediated recombination removed the FRT site flanked neomycin resistance cassette inserted into intron 10.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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