Allele/Variant

Destm1.1Ccrs

Species
Mus musculus
Symbol
Destm1.1Ccrs
Category
allele
Allele of gene
Des
Transgenic Constructs
None
Synonyms
  • Destm1(R349P)Cscl&Rfsr
Description
An R349P mutation (AGG to CCC) was inserted in exon 6 and a floxed neo cassette was inserted in intron 6 via homologous recombination. Cre mediated recombination removed the neo cassette. Immunoblot analysis indicates severely reduced expression of the mutant protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations