Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Ttr-SMYD3)1Ital
MGI:5749481Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Ttr-SMYD3)1Ital

Species
Mus musculus
Symbol
Tg(Ttr-SMYD3)1Ital
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The transgene contains the mouse transthyretin promoter driving expression of human SMYD3 (SET and MYND domain containing 3) with three hemagglutinin (HA) and three FLAG epitope tags at its C- and N-termini, respectively. Hepatic expression of the human protein is at least 15-fold that of the endogenous mouse protein.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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