Allele/Variant

Kcnk13em1(IMPC)H

Species
Mus musculus
Symbol
Kcnk13em1(IMPC)H
Category
allele
Allele of gene
Kcnk13
Transgenic Constructs
None
Synonyms
  • THIK-1 KO
Description
CRISPR mutagenesis induced a 1 nt insertion. This introduces a frameshift mutation into the codon for amino acid 14, leading to an abolition of the hydrophobic structure that normally forms the 1st transmembrane segment of the protein. A premature stop codon is generated after amino acid 68 in the open reading frame.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations