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Date: Tue Jan 28 2025
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Tg(Tek-Npr1)#Kkan
MGI:5750460
Mus musculus
Summary
Transgenic Constructs
Genomic Variant Information
Variant Molecular Consequences
Phenotypes
Disease Associations
Allele/Variant
Tg(Tek-Npr1)#Kkan
Species
Mus musculus
Symbol
Tg(Tek-Npr1)#Kkan
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
EC GC-A-Tg
Description
A 12.1 kb fragment of the mouse Tek gene including the promoter, enhancer and exons 1-3 of the 5' UTR drives expression of a mouse Npr1 cDNA in the vascular endothelium.
Additional Information
Literature
Transgenic Constructs
This allele contains 1 transgenic construct
Symbol
Expressed Components
Npr1
(Mmu)
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct
Genomic Variant Information
No data available
Variant Molecular Consequences
No data available
Phenotypes
Phenotype
Clear
Apply
Annotation details
Source
Clear
Apply
References
Clear
Apply
decreased metastatic potential
View
Name
Type
Experimental condition
Modifier
References
Tg(Tek-Npr1)#Kkan/0 [background:] involves: C57BL/6
genotype
PMID:25775533
MGI
PMID:25775533
decreased susceptibility to induced morbidity/mortality
View
Name
Type
Experimental condition
Modifier
References
Tg(Tek-Npr1)#Kkan/0 [background:] involves: C57BL/6
genotype
PMID:25775533
MGI
PMID:25775533
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Disease Associations
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