Gt(ROSA)26Sor^{tm47(CAG-EGFP*)Hze}

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Species

Mus musculus

Symbol

Gt(ROSA)26Sor^{tm47(CAG-EGFP*)Hze}

Category

allele

Allele of gene

Gt(ROSA)26Sor

Transgenic Constructs

None

Synonyms

• Ai47

Description

The Rosa-CAG targeting vector was designed with (from 5' to 3') a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), an FRT site, a loxP-flanked STOP cassette (with stop codons in all 3 reading frames and a triple polyA signal), triple GFP reporter genes (emerald, TagGFP (Aequorea macrodactyla GFP), and hrGFP (Humanized Renilla reniformis GFP)), a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability), a polyA signal, and an attB/attP-flanked PGK-FRT-Neo-polyA cassette. This entire construct was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations