Version: 8.0.0
Date: Tue Jan 28 2025
Runx2tm1.1Hkiy
MGI:5750985
Allele of Runx2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Runx2tm1.1Hkiy

Species
Mus musculus
Symbol
Runx2tm1.1Hkiy
Category
allele
Allele of gene
Runx2
Transgenic Constructs
None
Synonyms
  • Runx2-ITGA
Description
The I isoform-specific translation initiation site in exon 2 was replaced with a stop codon (TGA) and a floxed neomycin resistance cassette inserted downstream of exon 2. Cre-mediated recombination removed the selection cassette. RT-PCR analysis confirmed that total and variant transcript expression levels are restored in calvarial cells from E18.5 homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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