Ildr1^tm1.1Lwa

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Species

Mus musculus

Symbol

Ildr1^tm1.1Lwa

Category

allele

Allele of gene

Ildr1

Transgenic Constructs

None

Synonyms

• Ildr1^-

Description

A construct consisting of an FRT site, splice acceptor site, IRES, LacZ gene, loxP site neo cassette, FRT site and loxP site was inserted upstream of exon 2 and a loxP site was inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed the neo cassette and exons 2 and 3. LacZ expression was detected in the organ of Corti. qRT-PCR analysis confirmed the absence of mRNA expression in homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations