Ntn1^tm1.2Tek

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Species

Mus musculus

Symbol

Ntn1^tm1.2Tek

Category

allele

Allele of gene

Ntn1

Transgenic Constructs

None

Synonyms

• Netrin-1^-

Description

The targeting vector contains a FRT-flanked Neo selection cassette and a loxP site was inserted downstream of the first protein coding exon of the targeted gene, and another loxP site was inserted upstream of the first protein coding exon. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed the first protein coding exon. Western blot and immunohistochemical analysis of spinal cord confirmed the absence of protein expression.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations