Allele/Variant

Bcas1em1(IMPC)Tcp

Species
Mus musculus
Symbol
Bcas1em1(IMPC)Tcp
Category
allele
Allele of gene
Bcas1
Transgenic Constructs
None
Synonyms
None
Description
This allele produced from project TCPR0256 at The Centre for Phenogenomics by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGTGCCAATGGGCCGGTGGC. This resulted in an insertion of 1 bp (A on the -1 strand) at Chr2:170406531 (GRCm38) in exon 4 (ENSMUSE00001221352). This mutation is predicted to cause a frameshift with amino acid changes after residue 169 and early truncation 6 amino acids later (p.T170Nfs*8).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations