Nek2^em1(IMPC)Tcp

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Species

Mus musculus

Symbol

Nek2^em1(IMPC)Tcp

Category

allele

Allele of gene

Nek2

Transgenic Constructs

None

Synonyms

None

Description

This allele from project TCPR0309 was generated at the The Centre for Phenogenomics by injecting Cas9D10A mRNA and guide RNAs with spacer sequences GGTCCCGGTGAAGCACAGTG and CAGCAAACACAATGTCAAGC, which resulted in a 2-bp insertion +TC in Chromosome 1 positive strand 191822642 bp (GRCm38) and is predicted to cause a frameshift mutation with early truncation. c.465_466insTC; p.(L157Sfs*4)

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations