Pebp1^em1(IMPC)Tcp

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Species

Mus musculus

Symbol

Pebp1^em1(IMPC)Tcp

Category

allele

Allele of gene

Pebp1

Transgenic Constructs

None

Synonyms

None

Description

This allele produced from project TCPR0388 at TCP by injecting Cas9 mRNA and four guide RNAs with the spacer sequences TTTTAGTAGCGGCCATACTT, GAATTACCACTAATCTGCAT, GGCTATCTATCATCCGGACA, and ATTCTGCCGTCCTTACAGTA. This resulted in a 811-bp deletion from Chr5:117285622 to 117286432 insCA (GRCm38), exons ENSMUSE00000292490 & ENSMUSE00000292484. This mutation is predicted to cause a frameshift with amino acid changes after residue 47 and early truncation 11 amino acids later (p.M47Sfs*13). (GRCm38).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations