Tmem160^em1(IMPC)Tcp

---

Species

Mus musculus

Symbol

Tmem160^em1(IMPC)Tcp

Category

allele

Allele of gene

Tmem160

Transgenic Constructs

None

Synonyms

None

Description

This allele, from project TCPR0363, was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and two guide RNAs with spacer sequences AGTGTCCGAGCTGGATCGCG and ACTTCTGTCATCCGGCATTG. This resulted in a 1,033 bp deletion from Chr7:16453129 to 16454161 and 16 bp deletion from Chr7:16454205 to 16454221, from within exons ENSMUSE00000384664 and ENSMUSE00000198013, removing the splice donor site from the distal exon. This mutation is predicted to cause a frameshift with amino acid changes after residue 57 and early truncation 5 amino acids later (p.R57Wfs*7) (GRCm38).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations