Allele/Variant

Serpine1tm1.1Vlp

Species
Mus musculus
Symbol
Serpine1tm1.1Vlp
Category
allele
Allele of gene
Serpine1
Transgenic Constructs
None
Synonyms
  • PAI-1R101A/Q123K
Description
Exon 3 was replaced with a modified one in which nucleotide substitutions result in the amino acid substitutions of alanine for arginine at position 101 (R101A) and lysine for glutamine at position 123 (Q123K). Flp-mediated recombination removed the FRT- and loxP-flanked neomycin resistance cassette inserted downstream of the modified exon 3.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations