Allele/Variant

Tg(Ckm-DNAJB6_ib*F93L)#Ccwe

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

hDNAJB6a-F93L

Description

The human wild-type DNAJB6 isoform b with the most common Limb-girdle muscular dystrophy type 1D mutation, F93L, and with N-terminal V5 tags is under the control of the muscle-specific muscle creatine kinase promoter. Immunoblot analysis confirmed expression exclusively in skeletal muscle and not in heart, liver, kidney, or brain. Three lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

DNAJB6 (Hsa)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype	Annotation details	Source	References
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Disease Associations

Association	Disease Qualifier	Disease	Annotation details	Evidence	Source	References
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page