Allele/Variant

Prss36em1(IMPC)J

Species
Mus musculus
Symbol
Prss36em1(IMPC)J
Category
allele
Allele of gene
Prss36
Transgenic Constructs
None
Synonyms
  • Prss36em1J
Description
This allele from project Prss36-7695J-F6710 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GGTATTCAGCCTGGACAGCG, GAAGGTTGAGCTGCTGCGCA, ACCGAGCTTTGACTTCTAGG and GAGACCCTGGTAACTCGGGG, which resulted in a 352 bp deletion spanning exon 4 beginning at Chromosome 7 negative strand position 127,945,488 bp, CCGAGTTACCAGGGTCTCTG, and ending after CTGGCAATGCCACGCTGTCC at 127,945,137 bp (GRCm38/mm10). This mutation deletes exon 4 and 189 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 37 and early truncation 35 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations