Allele/Variant

Rasal1em1(IMPC)J

Species
Mus musculus
Symbol
Rasal1em1(IMPC)J
Category
allele
Allele of gene
Rasal1
Transgenic Constructs
None
Synonyms
  • Rasal1em1J
Description
This allele from project Rasal1-7697J-M1093 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences AGGCTAGAGTCTCATATGGT, TGGGGGCATGTGTAGACTCT, GAGAATGGGCTGATTCACAG and TGAACCGAATCACATATCAA, which resulted in a 481 bp deletion spanning exons 4-5 beginning at Chromosome 5 positive strand position 120,654,693 bp, TCTAGGAGTGTGTGTGTGAC, and ending after GAGGGAGAATGGGCTGATTC at 120,655,173 bp (GRCm38/mm10). This mutation deletes exons 4 and 5 and 305 bp of flanking intronic sequence including the splice acceptors and donors. This deletion of exons 4 and 5 is predicted to cause a change of amino acid sequence after residue 41 and early truncation 14 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations