Version: 8.0.0
Date: Tue Jan 28 2025
Thrbtm1Ehs
MGI:5784668
Allele of Thrb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Thrbtm1Ehs

Species
Mus musculus
Symbol
Thrbtm1Ehs
Category
allele
Allele of gene
Thrb
Transgenic Constructs
None
Synonyms
  • TRbeta147F
Description
Exon 6 was replaced with a modified one in which an A-to-T point mutation results in the amino acid substitution of tyrosine with phenylalanine at position 147 (p.Y147F). A loxP site flanked neomycin resistance gene cassette was inserted into intron 6. Quantitative real-time PCR analysis revealed normal mRNA levels in the cortex of P12-P17 homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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