Mlkl^m2Btlr

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Species

Mus musculus

Symbol

Mlkl^m2Btlr

Category

allele

Allele of gene

Mlkl

Transgenic Constructs

None

Synonyms

• secro

Description

ENU-induced T to C transition at base pair 111,315,567 (v38) on chromosome 8, or base pair 22,890 in the GenBank genomic region NC_000074. The mutation is within intron eight, 25 base pairs away from exon 9 (out of 11 total exons). The effect of the mutation on the mRNA sequence and protein expression is unknown. In the event of exon 9 skipping, the aberrant transcript would have a deletion of the 50 base pair exon 9, leading to a frame-shift occurring after amino acid 383 of the protein (isoform 1), and termination after the inclusion of two aberrant amino acids.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations