Ptchd1^tm2.2Gfng

---

Species

Mus musculus

Symbol

Ptchd1^tm2.2Gfng

Category

allele

Allele of gene

Ptchd1

Transgenic Constructs

None

Synonyms

None

Description

A targeting vector containing a FRT-site flanked NEO selection cassette was used to insert loxP sites flanking exon 2. This selection cassette was inserted downstream of exon 2 of the targeted gene, and another loxP site was inserted upstream of exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. In situ hybridization confirmed the absence of full-length mRNA in the brain.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations