Allele/Variant

Adamtsl4em1(IMPC)J

Species
Mus musculus
Symbol
Adamtsl4em1(IMPC)J
Category
allele
Allele of gene
Adamtsl4
Transgenic Constructs
None
Synonyms
  • Adamtsl4em1J
Description
This allele from project Adamts14-8000J-M9624 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GGTGGCTTCACATTCCCACT, CTAGGTTATTAGACTAAGAG, AGGGACTGTGAACTGTTGGA and CGAGGGGTGGGGGACATCAG, which resulted in a 269 bp deletion beginning at Chromosome 3 negative strand position 95,685,133 bp GTTGGAAGGGGTCTGGCAAG, and ending after TGGCTTCACATTCCCACTGG at 95,684,865 bp (GRCm38/mm10). This mutation deletes exon 3 and 112 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 161 and early truncation 58 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations