Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Prnp-PFN1)34Zxu
MGI:5796265Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Prnp-PFN1)34Zxu

Species
Mus musculus
Symbol
Tg(Prnp-PFN1)34Zxu
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Prp-PFN1WT
Description
The transgenic construct contains a human profilin 1 cDNA sequence with a V5 tag (45 bp) fused to the N-terminus and inserted between exon 2 and exon 3 of mouse prion protein gene at a unique XhoI site in the MoPrP.Xho plasmid vector. Founder line 34 was found to have stable high expression predominantly in the central nervous system.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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