Allele/Variant

Agfg2em1(IMPC)J

Species
Mus musculus
Symbol
Agfg2em1(IMPC)J
Category
allele
Allele of gene
Agfg2
Transgenic Constructs
None
Synonyms
  • Agfg2em1J
Description
This allele from project Agfg2-8101J-F2486 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TCCCAAAAGAAACTTTTGGG, CTCAAAGCTTTGCTACCAAG, GCTGTGGCAGGTGAGTGCAC and CACAGAAGATGGTCTCAGTC, which resulted in a 562 bp deletion beginning at Chromosome 5 negative strand position 137,668,182 bp, GCAGGGCTCTACCACTGAGC, and ending after CATGCCACTTGGTAGCAAAG at 137,667,621 bp (GRCm38/mm10). This mutation deletes exon 2 and 468 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 74 and early truncation 14 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations