Dusp18^em1(IMPC)J

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Species

Mus musculus

Symbol

Dusp18^em1(IMPC)J

Category

allele

Allele of gene

Dusp18

Transgenic Constructs

None

Synonyms

• Dusp18^em1J

Description

This allele from project Dusp18-8276J-M2282 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences AGAGACCGTGAACAATGGAA, GGTCTTTTCACACAGAGGAA, GAACTCCTCAGGCCGCAGAG and GCAAATCCCTAAAACAGGTA, which resulted in a 4631 bp deletion beginning at Chromosome 11 positive strand position 3,896,766 bp CATTGTTCACGGTCTCTCTG, and ending after AAGGGAACTCCTCAGGCCGC at 3,901,396 bp (GRCm38/mm10). This mutation deletes exon 2, which is the only translated exon, along with 277 bp of flanking intronic sequence, including the splice acceptor and donor, so it is predicted to result in a complete null.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations