Allele/Variant

Tg(PDGFB-SNCA/EGFP)78Ema

Species
Mus musculus
Symbol
Tg(PDGFB-SNCA/EGFP)78Ema
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • PDNG78
Description
The human alpha-synuclein cDNA without a stop codon is fused to the 5' end of EGFP and under the control of the PDGF-beta promoter. Five lines were obtained and the highest expresser lines, 75 and 78, were selected. Levels of human alpha-synuclein mRNA expression are equivalent to 3-fold the human brain levels in this line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations